Persist - We build long-lasting drugs 50% faster 💊

TLDR

Persist helps pharma make drug injections that last up to 1 year.

Using robotics & AI, we reduce a 5-year drug formulation process to ~2 years.

Contact Us (founders@persist-ai.com) for a case-study formulation

To make injections we encapsulate drugs inside injectable microspheres made with FDA-approved materials.

Left: Image of a ~37 um microsphere made by our robotics

Right: A Schematic showing how encapsulated drugs are released over 1 year so patients don’t take as many injections.

🤔THE PROBLEM

For chronic diseases, most patients prefer 1 injection/yr rather than multiple injections per week.

However, making a long-lasting injection takes a lot of trial and error and the time between iterations is long.

Key challenges include:

• Using manual work & intuition is slow: Typical teams manually mix and match chemicals to optimize the amount of drug that’s loaded into the spheres and the rate of release of drug
• Trial and error is cumbersome: Because changing one variable may have multiple effects
• Scale-up is unpredictable: Even if something works at a small scale, batch-to-batch consistency during scale-up is uncertain because production is done in large reactors

💡OUR SOLUTION

We utilize custom robotics and AI to solve the problems with building microspheres.

• We automatically mix & optimize formulations: We use a closed-loop robotics + AI approach so there’s minimal manual work
• We reduce trial & error with AI predictions: We generate 50x more data than most formulation teams and use that data to train AI. This unique data enables us to make better predictions than others.
• We build small batches, faster: So we can QC batches more frequently and scale up predictably

❤️OUR ASKS

Introduce us to friends who work in Pharma. Email founders@persist-ai.com

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