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Cofactor Genomics

Cofactor closes the precision medicine gap with predictive diagnostics

Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data. The team recently had their technology validation peer-reviewed by the organizations that set standards for diagnostic technology (CAP, AMP) and is publishing in the Journal of Molecular Diagnostics. In addition, the team made news when Cancer Physicians who sit on the committee for patient treatment guidelines (NCCN) presented a clinical study using Cofactor’s technology showing superiority in predicting the patients who will respond to immunotherapy. This initial application is an acute problem recognized widely in the rapidly developing immunotherapy industry and represents north of a billion dollar TAM. After a number of recent key milestones, the team is taking the technology more broadly to 50% of cancers diagnosed in the US. Current investors include Menlo Ventures, DCVC, and Ascension Ventures (this last investor representing the funding arm for 13 National U.S. Healthcare Systems).

Cofactor Genomics
Founded:2015
Team Size:13
Location:St. Louis, MO

Active Founders

Dave Messina, Founder/COO

Dave Messina has spent the last 20 years in computational biology and human genetics. He contributed to the Human Genome Project at Washington University in Saint Louis, mapped disease genes at the University of Chicago, and co-developed the first comprehensive atlas of human transcription factor genes. As COO of Cofactor Genomics, Dave leads regulatory and reimbursement efforts for the company, driving the implementation of RNA-based diagnostics and their clinical application.

Jarret Glasscock, Founder/CTO

Jarret Glasscock
Jarret Glasscock
Cofactor Genomics