Manufacturing Startups funded by Y Combinator (YC) 2025

January 2025

Browse 46 of the top Manufacturing startups funded by Y Combinator.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Relativity Space
    Relativity Space (w2016)Active • 1,000 employees • Los Angeles, CA, USA
    Relativity is building humanity’s multiplanetary future. We invented a new approach to design, build, and fly our own rockets, starting with Terran 1 – the world’s first entirely 3D printed rocket, and Terran R, our next generation medium-heavy lift fully reusable launch vehicle. As a vertically integrated technology platform, Relativity is at the forefront of an inevitable shift toward software-defined manufacturing. By fusing 3D printing, artificial intelligence, and autonomous robotics, we are pioneering the factory of the future. Disrupting 60 years of aerospace, Relativity offers a radically simplified supply chain, building a rocket with 100x fewer parts in less than 60 days. We believe in a future where interplanetary life fundamentally expands the possibilities for human experience. Our long-term vision is to upgrade humanity’s industrial base on Earth and on Mars.
    machine-learning
    space-exploration
    rocketry
    3d-printing
    manufacturing
  • Vista Power
    Vista Power (w2024)Active • 3 employees • San Francisco, CA, USA
    Vista installs energy storage and solar at commercial and industrial properties for $0 upfront, helping businesses save up to 30% on their energy bills. The founding team previously worked at SpaceX, Rocket Lab, NASA and Firefly.
    energy-storage
    b2b
    sustainability
    manufacturing
    renewable-energy
  • Zelos Cloud
    Zelos Cloud (s2023)Active • 3 employees
    Zelos Cloud is accelerating electronics product development with powerful tools for emulation, tracing, and automated testing on real microcontrollers in the cloud. As firmware engineers, we spent years developing and shipping products at scale. Between batteries, bootloaders and brain implants, we've seen it all. Our mission is to build the tools we wish we had to enable teams to ship higher quality products, faster.
    hard-tech
    manufacturing
    data-visualization
  • Solugen
    Solugen (w2017)Active • 200 employees • Houston, TX, USA
    Solugen is decarbonizing the chemistry of everyday life with enzymes and innovative metal catalysts. Our new to the world Bioforge platform technology can produce high value chemical goods that are biobased and carbon negative, at cost on par with current technologies. We are making sustainable chemistry accessible to all living things, to ensure a prosperous world exists for generations.
    manufacturing
    climate
    climatetech
    biotechnology
    industrial
  • Atomic Industries
    Atomic Industries (w2021)Active • 25 employees • Detroit, MI, USA
    Atomic's mission is to replicate high-skill trade knowledge of tool and die makers into AI that powers new manufacturing systems which are orders of magnitude more productive.
    artificial-intelligence
    hard-tech
    manufacturing
  • Mobius Materials
    Mobius Materials (s2020)Active • 6 employees • San Francisco, CA, USA
    Mobius is the safe spot market for electronic components like microcontrollers and capacitors. We help electronics manufacturers buy and sell chips quickly, safely & at market prices.
    hardware
    manufacturing
    supply-chain
    semiconductors
  • Lucid Bots
    Lucid Bots (s2019)Active • 26 employees • Charlotte, NC, USA
    At Lucid, we are a B2B robotics provider for dull, dirty, and dangerous jobs, starting with the cleaning industry, which has a 200% annual turnover rate. Our primary product is a drone that can clean anything from windows to roofs to stadium domes to industrial tanks. Our drones can clean up to 8x faster. Due to customer demand, we also launched a ground-based pressure-washing robot to complement our cleaning drone. We support customers around the country who use our robots every day to clean properties with great safety and efficiency. We engineer, manufacture, and support our technology from a 20,000 sqft headquarters in Charlotte, NC.
    robotics
    drones
    manufacturing
    aerospace
    self-driving-vehicles
  • AON3D
    AON3D (w2017)Active • 40 employees • Montreal, QC, Canada
    AON3D is a rapidly growing startup on a mission to put industrial 3D printing capabilities into the hands of those who need it most. Our technology has made it 10 times cheaper than before to 3D print with advanced thermoplastics, and we continue to push the boundaries on commercializing new materials for 3D printing. Our customers span the globe and are pioneers in the application of 3D printing in their field – from automotive tooling to aircraft interiors, foundry molds to public art installations, prosthetics to guides for radiation and surgical oncology. AON3D is a graduate of Y-Combinator and venture-backed by top investors from Silicon Valley.
    hardware
    3d-printing
    manufacturing
  • AminoAnalytica
    AminoAnalytica (s2024)Active • 3 employees • San Francisco, CA, USA
    Biotechs use proteins found in nature, such as enzymes in bacteria or peptides in lizards, in a wide range of applications from chemical manufacturing to therapeutics. However, these naturally occurring proteins aren't optimized for industry. At AminoAnalytica, we specialize in AI-powered protein optimization. Using our proprietary computational tools, we can improve the properties of a target protein sequence, from the stability of therapeutic peptides to the activity of industrial enzymes. When we optimize a protein, it’s not just a theoretical suggestion—we work with labs to ensure that it’s functional, stable, and ready to change the world.
    synthetic-biology
    biotech
    manufacturing
    climate
    industrial
  • camfer
    camfer (s2024)Active • 3 employees • San Francisco, CA, USA
    We’re building the first AI mechanical engineer that collaborates with humans to do design tasks end-to-end. Human engineers can talk to camfer to build, test, and iterate 3D designs natively on CAD platforms.
    generative-ai
    hardware
    productivity
    manufacturing
    ai
  • Future Fields
    Future Fields (s2020)Active • 34 employees • Edmonton, AB, Canada
    Future Fields has developed the world's first multicellular advanced biomanufacturing platform for the production of the most challenging recombinant proteins. We help companies in biotech, life sciences, and pharma by manufacturing their proteins.
    biotech
    manufacturing
    climate
  • Forge Automation
    Forge Automation (w2025)Active • 7 employees • Toronto, ON, Canada
    Forge Automation runs software enabled factories that deliver custom metal parts in four days or less. Instead of mechanical engineers having to wait two to three weeks for their low volume CNC parts, they can simply upload a CAD model on our platform and we will ship it out in four days or less. We aim to give mechanical engineers the "Amazon experience" for custom metal parts.
    hard-tech
    hardware
    robotics
    manufacturing
    industrial
  • Autumn Labs
    Autumn Labs (s2024)Active • 3 employees • San Francisco, CA, USA
    Autumn Labs delivers a developer-friendly platform for monitoring and managing modern manufacturing lines. Seamlessly integrating with robotic stations—automated test stations, robotic assembly cells, and industrial arms—it ensures full traceability, live data monitoring, and secure data transport. We prioritize streamlining factory operations, boosting production quality, and preventing supply chain disruptions, all while offering an effortless onboarding experience for engineers and manufacturers.
    hardware
    robotic-process-automation
    saas
    robotics
    manufacturing
  • Synvivia
    Synvivia (s2016)Active • 4 employees • Berkeley, CA, USA
    Synvivia applies chemical control over cell behavior. This allows us to optimize biomanufacturing of high-value biopharmaceutical products.
    artificial-intelligence
    synthetic-biology
    biotech
    manufacturing
    drug-discovery
  • Distro
    Distro (s2024)Active • 7 employees • Palo Alto, CA, USA
    Distro is the all-in-one AI-powered sales platform for counter staff and inside sales at industrial wholesale distributors (HVAC/R, plumbing, electrical, and more).
    artificial-intelligence
    saas
    b2b
    manufacturing
    supply-chain
  • SRTX
    SRTX (w2018)Active • 150 employees • Montreal, QC, Canada
    SRTX builds new materials and software to enable better textiles. SRTX is best known for its first technology, Sheertex, a knit made from one of the world's strongest polymers which has disrupted hosiery through impossibly strong pantyhose.
    hard-tech
    smart-clothing
    consumer
    manufacturing
  • Sourcify
    Sourcify (w2018)Active • 15 employees • San Diego, CA, USA
    Sourcify is a profitable high growth sourcing platform that helps ecommerce brands and Fortune 500s manufacture products in Asia.
    manufacturing
    supply-chain
  • Soff
    Soff (s2024)Active • 2 employees • San Francisco, CA, USA
    Soff is a supply chain OS for manufacturing companies. We unify supply chain data and automate core workflows, such as data entry, requesting quotes, comparing quotes, and issuing purchase orders. Our customers save dozens of hours a week spent on repetitive manual tasks.
    b2b
    manufacturing
    supply-chain
    procurement
    enterprise-software
  • Jiga
    Jiga (w2021)Active • 15 employees • San Francisco, CA, USA
    Jiga partners you directly with vetted manufacturers so you can communicate and get competitive, reliable human quotes. Our platform speeds up your workflow from request to delivery, so you can build great products faster than ever.
    b2b
    manufacturing
    supply-chain
  • Diode Computers, Inc.
    Diode Computers, Inc. (s2024)Active • 2 employees • New York, NY, USA
    Diode automates hardware design, like hiring a senior electronic engineer for your projects. We use generative AI models to create and manufacture custom printed circuit boards in minutes, not weeks.
    generative-ai
    saas
    manufacturing
    electronics
  • Terra
    Terra (s2024)Active • 2 employees • New York, NY, USA
    Enter Terra, a new world of product building. Connect with suppliers, expedite sampling, and track production in real-time, removing the uncertainties of overseas manufacturing.
    manufacturing
    supply-chain
    procurement
    enterprise-software
  • Standard Data
    Standard Data (s2024)Active • 2 employees • San Francisco, CA, USA
    Standard Data builds interactive copilots for highly skilled manufacturing roles. U.S. manufacturing is in crisis. Despite surging growth, by 2030 the United States will have 4 million unfilled roles. Automation will not be capable of replacing these skilled roles - to create a safe, prosperous future, we must secure the next generation of manufacturing talent.
    education
    recruiting
    manufacturing
  • Assembly
    Assembly (s2015)Active • 12 employees • Redwood City, CA, USA
    Crowdfunding has fueled an increase in innovative product companies turning to Chinese factories for production. Yet, Chinese factories seem undifferentiated because they all make the same, unverifiable claims of excellence. This results in competition centered on price. Factories are forced to under-bid contracts to win business, but often, they later surprise the customer with quality problems and delays. This process is broken. We install cameras and remote monitoring software on the assembly line, and this ensures compliance with test protocol, improves quality, reduces liability, and helps fight warranty fraud. We charge a nominal per-unit fee to the OEM and revenue share with the factory when they demonstrate compliance with quality standards (whether units pass or fail). It encourages better behavior from factories and rewards those who perform with an audit trail of good performance that helps them win new foreign business. On average, defect rate will fall 75% within 5 months of deploying Assembly at a factory.
    logistics
    manufacturing
    china
  • Praxis AI
    Praxis AI (f2024)Active • 2 employees • New York, NY, USA
    Praxis AI builds manufacturing specific agents capable of reasoning and processing complex situations. Our engineering copilot predicts and prevents machine failures in real time by solving problems the same way an engineer would. Our agents have access to and make sense of the structured and unstructured data that exists at factories including machine sensor data, maintenance manuals and work orders. Our simplified interface enables manufacturing teams with minimal AI knowledge to create custom complex workflows on the machinery they know is critical to their operations. Early results have shown that Praxis can help manufacturers reduce their unplanned production downtimes by as much as 25%. Existing solutions focus on dashboards and complex charts. We know that dashboards don't cut costs, actions do.
    artificial-intelligence
    iot
    manufacturing
    data-science
    ai-assistant
  • OpsNinja
    OpsNinja (s2023)Active • 8 employees • New York, NY, USA
    OpsNinja is your e-commerce brand's product quality control department. Built by sellers, and trusted by 800+ brands. Are you a Shopify or Amazon seller? Sign up in 30 seconds to start monitoring your product quality for free!
    artificial-intelligence
    logistics
    manufacturing
    e-commerce
    supply-chain
  • Tiny
    Tiny (f2024)Active • 3 employees • Singapore
    At Tiny, we’re building a new kind of ERP system for factories where AI agents automate repetitive workflows. Made for the four million factories still primarily relying on Excel. LLMs now unlock their troves of siloed unstructured data. We see a massive opportunity to build a compound startup and, beyond that, tap into network effects to unlock just-in-time manufacturing across entire supply chains.
    saas
    b2b
    workflow-automation
    manufacturing
    enterprise-software
  • AiSupervision
    AiSupervision (w2022)Active • 13 employees • Mannheim, Germany
    We make the operating system to track, manage and improve production in factories with many workers. We automate what the best supervisors would do if they watched everything that’s happening inside your factory.
    manufacturing
    industrial
  • Proglix
    Proglix (w2023)Active • 25 employees • Jakarta, Indonesia
    Proglix is a marketplace for small and medium manufacturers to buy metal and steel raw materials in Indonesia. With our platform, customers can easily order domestic and import raw materials with cheaper price, no minimum order quantities, 2x faster in SLA and real time inventory stock.
    marketplace
    b2b
    manufacturing
    e-commerce
  • Forerunner AI
    Forerunner AI (f2024)Active • 2 employees • San Francisco, CA, USA
    Forerunner is your aerospace, defense, and hardware engineering copilot, helping you beat tight deadlines by automating critical engineering workflows. Our secure AI agents access data from tools like Atlassian Suite and Microsoft Office, then collaborate with hardware engineers to accelerate design and analysis.
    artificial-intelligence
    manufacturing
    aerospace
  • Fabricate
    Fabricate (f2024)Active • 2 employees
    Hardware engineers spend a quarter of their time just figuring out how to get their parts made, and from who. Fabricate builds procurement software for hardware teams. We help engineers manage manufacturing feasibility and procurement across their suppliers, whether they're getting parts custom manufactured or buying them off-the-shelf.
    artificial-intelligence
    b2b
    manufacturing
  • Thread
    Thread (w2023)Active • 2 employees • Chattanooga, TN, USA
    Thread simplifies the business processes for manufacturing companies. Upload your company documents to our secure platform, collaborate seamlessly across your organization to respond to vendor questionnaires.
    developer-tools
    b2b
    manufacturing
    enterprise
    ai
  • Vastrm (s2012)Active • 2 employees • Burlingame, CA, USA
    Vastrm Fashion™ (pronounced vas' trum) Vastrm was started to solve a basic problem: Shirts that don’t fit well! Mass produced shirts were meant to accommodate a wide variety of body types with one standard size, and different brands have different sizing standards, making shopping difficult--many men must shop in 4 - 5 different stores before finding a shirt that actually fits! By providing a home try on program and giving the ability to make custom fit adjustments to all of their apparel, Vastrm allows its customers to finally hone in on and find the perfect fit for their unique body types. Tang came up with the idea for Vastrm, which is a Sanskrit word for cloth, when a customer told him he had purchased a perfect shirt in Italy and has never been able to find the same fit again. He was considering flying back to Italy to track the shirt maker down, but Jonathan managed to adjust Vastrm shirts to the same fit.
    manufacturing
    apparel
    customization
  • Serial
    Serial (w2023)Active • 2 employees • San Francisco, CA, USA
    Serial is software to help manufacturers root cause problems in minutes not days and avoid millions in liabilities. Our solution integrates with data sources from any production line, enabling engineering & operations teams to ask questions about their manufacturing data and instantly get answers. Serial will become the single source of truth for manufacturing data. Our founding team has 10+ years of manufacturing and product design experience from Apple, Tesla, and more. We have suffered this problem firsthand and are building the tool to fix it.
    saas
    analytics
    manufacturing
  • RMFG
    RMFG (s2021)Active • 2 employees • Fort Worth, TX, USA
    We're building autonomous sheet metal factories. Sheet metal is a large ($200b+ in the US) industry heavily reliant on human labor. If you're building something in the real world, it's almost a certainty that you will use sheet metal in some capacity. It's used in automotive manufacturing, aerospace, consumer goods, defense, and many more verticals. The industry mostly operates the same way it has for the last 50+ years. We're making a 10x better experience for people to get sheet metal parts manufactured. We are vertically integrated and build everything from our quoting engine to the physical automation inside of our factory. Factories should own automation as a core in-house skill. Today we sell laser cut and bent sheet metal parts. Users can get instant quotes through our website (and eventually through integrations build on top of our API). We build custom internal software to command and control the operations of the factory. Right now we are actively working on fully automating the production of laser cut parts including scheduling, material movement, laser configuration, etc. Orders will be able to come in, and our software will control the factory and output parts ready to ship.
    robotics
    manufacturing
    industrial
  • Sensible Biotechnologies
    Sensible Biotechnologies (s2021)Active • 22 employees • Oxford, UK
    The future of mRNA therapeutics is hampered by manufacturing challenges and unless solved, its exciting potential may never be realised. Sensible enables the next generation of mRNA medicines by turning living cells into factories producing abundant, highly stable and non-immunogenic mRNA in a scalable and cost-effective way.
    synthetic-biology
    biotech
    manufacturing
    therapeutics
    biotechnology
  • Dime
    Dime (w2024)Active • 3 employees • New York, NY, USA
    Dime enables manufacturers to utilize their telemetry data to anticipate and prevent equipment and hardware product failures. Our AI agent identifies patterns of key failure modes and builds ML models to prevent them.
    saas
    manufacturing
    enterprise-software
  • Draftaid
    Draftaid (w2024)Active • 3 employees • Toronto, ON, Canada
    DraftAid is the world's first generative AI for CAD manufacturing drawings, akin to GitHub Copilot but for CAD. It drastically shortens drawing creation time, turning hours into seconds. Every product that is manufactured - from construction to aerospace, automotive, durable goods, and electronics—relies on drawings. Currently, engineers and designers painstakingly make these essential drawings manually. Draftaid streamlines this process saving teams millions in time and quality. The idea was born out of Abdullah's experience as a mechanical design team member, where he created thousands of drawings and longed for a more efficient process. Partnering with Tahsin, a neighbour with a PhD in AI, and Mohammed, a seasoned engineering VP with experience in construction software, they turned the dream into reality. Since their launch in August, DraftAid has engaged customers through targeted outreach and word-of-mouth, securing paid pilots with subsequent contracts valued at $150,000. Be a part of ushering in the new era of CAD designs!
    construction
    design
    manufacturing
    architecture
    ai-assistant
  • Axross Pte Ltd
    Axross Pte Ltd (w2022)Active • 10 employees • Singapore
    At Axross, we specialize in delivering AI-driven HVAC control systems designed to enhance energy efficiency and reduce operational costs for manufacturers. Our solutions are tailored to meet the stringent requirements of industries, where maintaining precise environmental conditions is critical. With a team of experts in AI, data science, and industrial systems, Axross is committed to providing reliable, scalable solutions that help manufacturers achieve their energy efficiency goals and support sustainable practices.
    b2b
    manufacturing
    ai
  • Industrial Next
    Industrial Next (w2022)Active • 9 employees • San Francisco, CA, USA
    We bring Tesla autonomous manufacturing to every automaker and other producers. At Tesla, we were the core autonomous factory team and we’re now building the smart cameras and robotic guidance tools that provided the main advantages at Tesla
    hard-tech
    robotics
    manufacturing
    ai
  • CUTR
    CUTR (w2022)Active • 22 employees • Amsterdam, Netherlands
    Look around you - everything you see that was made with wood a designer conceived and then a woodworker has made. Most of the time, something went painfully wrong. 60% of the $1.4T global woodworking market is serviced by small businesses with inefficient, manual processes - Cutr is digitising their workflow. This market is massive, chaotic and surprisingly manual. Woodworkers are mostly offline, hard to find and even harder to vet. They need help with critical back-of-house jobs like quoting and capacity planning. Customers have no idea where to find them and need help asking the right questions & providing the right info to get their job produced correctly. Cutr solves discovery, pricing, payments and workflow for the woodworking market. Our users simply upload a file, accept an instant quote, and get their parts delivered. To make that possible we do the heavy lifting: filechecks, automated quoting, matchmaking, creating job packages, tracking changes & updates, logistics and payments. Cutr saves time, cuts costs and ensures quality with a smooth workflow.
    marketplace
    manufacturing
  • Versable
    Versable (w2022)Active • 3 employees • Los Angeles, CA, USA
    Auto parts retailers get product data from hundreds of manufacturers that is inaccurate and inconsistent, often with big gaps in key values. They currently have a team of "catalog managers" who are required to process and enhance this data line by line, resulting in a week to months long lag between receiving product data and actually being able to start generating revenue from those products. Versable leverages AI to scan the web for tens of millions of auto parts listings, and uses a fine-tuned LLM with RAG to instantly process, enhance, and transform data. With just a part number, Versable is able to generate market-ready titles, product descriptions, and specs, in any format that's needed.
    artificial-intelligence
    manufacturing
    data-engineering
    automotive
  • IoTFlows Inc
    IoTFlows Inc (w2022)Active • 2 employees • Atlanta, GA, USA
    IoTFlows provides comprehensive visibility and valuable insights into manufacturing shop floors. Leveraging artificial intelligence to monitor and analyze the performance of machines based on their vibration and acoustics data, we help manufacturers to identify issues and inefficiencies in the production process and make data-driven decisions to improve performance.
    artificial-intelligence
    deep-learning
    machine-learning
    iot
    manufacturing
  • Olympian Motors
    Olympian Motors (w2022)Active • 10 employees • New York, NY, USA
    Olympian Motors is an electric vehicle company, based in New York. We are manufacturing electric vehicles with our innovative 'modular' vehicle & drivetrain architecture (MVDS), providing Olympian with strong cost and lead-time advantages compared to legacy automakers like Tesla and Ford. Olympian is disrupting 120+ years old automotive industry and targeting to capture 7% market share in the U.S. automotive market by 2030. We changed the status-quo in automotive design, and bring aesthetic, color, experience and minimalism back to the cars. Olympian MVDS has a 'Lego-like' architecture and built on 4-core-hardware and 2-software modules. We achieved 80% reduction in tooling & machinery costs and built ~60% faster production lead time. We aim to reinvent the car manufacturing and bringing agility, speed and cost-efficiency back to the U.S. automotive industry. + Received 214 pre-orders for Olympian Model O1 ($17M+ pre-booked revenue) + Started manufacturing our EVs in Brooklyn & Detroit facilities. 2023 capacity: 320 vehicles + Pending traffic approval from NHTSA + Modular vehicle/drivetrain + Modular manufacturing: 4-hardware + 1-sofware modules. ~60% faster production lead time. 80% reduction in tooling, fitment and labor expenses. + Commercial Launch in Q3/2023. Unlike other EV companies, we don't waste time/resources. (It took 9+ years for Lucid and 11+ years for Rivian to make their first shipment). + Super-competitive battery efficiency in urban areas (Olympian early prototypes achieved slightly better miles/kwh efficiency than Tesla Model 3 and Rivian). + Carbon-sequestered and recyclable materials for +4% of vehicle components. Olympian rejects today's commoditized and banal car experience. + We challenge the status-quo in automotive. + We prioritize aesthetic, nature and minimalism. + We use steel and wood in Olympian cars rather than not cheap plastic and toxic chemicals. + We have minimalistic cockpit, powered by Olympian Operating System (OOS)
    consumer
    manufacturing
    climate
    transportation
    electric-vehicles
  • Cerrion
    Cerrion (s2022)Active • 9 employees • Zürich, Switzerland
    Cerrion helps manufacturers automatically detect, understand and eliminate problems on their production lines using video-based Computer Vision. Our AI leverages standard CCTV cameras and learns how a manufacturing process looks like when things are going well and can automatically detect and track problems in real-time. For example, one of our customers, a Pepsi supplier producing 500 bottles per minute now automatically detects and reacts to a fallen bottle before it starts blocking their production line.
    deep-learning
    computer-vision
    video
    manufacturing
    ai
  • Sculpt
    Sculpt (s2022)Active • 2 employees • San Francisco, CA, USA
    Artificial Intelligence that converts manufacturing drawings into costing quotations in minutes, not weeks.
    b2b
    manufacturing
    enterprise
  • VIDA & Co. (s2017)Acquired • 11 employees • San Francisco, CA, USA
    VIDA is the story of the rich, beautiful, interconnected world in which we live. It is the story of contemporary life and of mindful, global citizenship. VIDA is a collaboration amongst global citizens - from a designer in Milan, to a producer in Karachi, and a consumer in San Francisco – we are a global partnership of co-creators. VIDA presents an alternative to the homogeneous, disposable products that increasingly dominate retail. We produce only that which is purchased, bringing into the world only items that are wanted. We are using innovations in design and technology to make quality accessible again. We produce with the highest ethical standards, respecting the makers of the products we bring into our lives. We believe beautiful products should create beauty every step of the way.
    marketplace
    manufacturing