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Relevium Medical

Platform injectable gel based therapeutic for osteoarthritis

Relevium Medical is developing an injectable gel for knee osteoarthritis. Approximately half the population will be diagnosed with this pain and progressive disease. Right now, patients have to undergo not only repeat injections to control their pain, but also have to take strong oral medications. Because the disease is progressive and only gets worse over time, many patients end up on highly addictive, high-dose opioids. To date, we have secured $3.7 million in non dilutive funding and completed preclinical testing. We demonstrated that our drug is safe, selectively blocks nerves that transmit pain, and provides pain relief that lasts four times as long. Insurance currently pays $770 per six-monthly treatment for knee osteoarthritis. With 5 million patients in the US, this represents a $7.7 Bn market opportunity. This platform biotherapeutic can also be used to treat other joints affects by osteoarthritis such as the hip and ankle, where the same problems exist in treatment care.
Relevium Medical
Founded:2019
Team Size:5
Location:Galway, Ireland
Group Partner:Surbhi Sarna

Active Founders

Alison Liddy, Founder

Alison is CEO and Founder at Relevium Medical. Alison holds qualifications in Chemistry and Biochemical Engineering (M.Sc. & Ph.D.). She has worked for major multinational companies including ROCHE, Cook Medical and Boston Scientific; and completed the BioInnovate Fellowship in the prestigious Stanford BioDesign-affiliated program at NUI Galway, Ireland. She is the named inventor on over 20 patent publications and the winner of the Science Foundation of Ireland’s €1 million innovation prize.
Alison Liddy
Alison Liddy
Relevium Medical

Company Launches

The problem: The chronic pain condition Knee osteoarthritis (OA) affects over 250 million people globally, creating significant social and healthcare challenges, with untreated pain being the #1 patient complaint.  In the absence of effective long-term injectable treatments, millions of patients rely on damaging oral medications.

Capsaicin, offers long-lasting, selective pain relief for chronic pain via molecular ablation of pain-sensing nerves only. Despite FDA approval and proven safety and efficacy, its adoption is limited by intense burning pain post-administration, requiring over 1.5 hours of clinic management and making it intolerable for many patients. This has restricted the use of an otherwise highly effective treatment for chronic pain.

Our solution: RM-010 was specifically developed to address the burning pain associated with Capsaicin. Relevium Medical has engineered an innovative drug delivery system that gradually releases Capsaicin into the knee joint, carefully maintaining concentrations below the threshold that triggers burning pain while sustaining levels high enough to achieve full nerve ablation. This breakthrough offers patients a highly tolerable, effective, and safe treatment, delivering long-lasting pain relief with a significantly improved experience. RM-010 is designed for seamless integration into clinical workflows, allowing physicians to administer the therapy in 5 minutes. It provides a practical, patient-friendly solution for effectively managing knee osteoarthritis pain, setting a new standard in treatment care.

Who are are: Relevium Medical, headquartered in Galway, Ireland, is a pioneering pharmaceutical company driven by a passionate team of chemists, neuroscientists, pharmacists, and industry experts. United by a shared mission, the team is dedicated to developing novel solutions to improve the lives of people living with chronic pain.

Interested in hearing more: Get in contact at info@Relevium-Medical.com

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