Supply Chain Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2025

Founded in 2013, we believe trade can move the human race forward. That’s why our mission at Flexport is to make global trade easy for everyone. What the internet has done for bits and bytes, Flexport is doing for physical goods: giving every business the ability to connect to any customer, wherever they are in the world. That sounds pretty straightforward, but a fragmented and inefficient global supply chain has held the world back from untapped growth and innovation. By connecting everyone in the global economy we can unlock commerce, creativity, and human progress. To do so, we’re building the platform for global logistics—empowering buyers, sellers and their logistics partners with the technology and services they need to grow and innovate. Today, we work with more than 40,000 customers and their suppliers across industries like manufacturing, retail, electronics, consumer goods, tech, apparel, and beauty. Companies of all sizes—from emerging brands to Fortune 500s—used Flexport technology to move nearly $19B of merchandise across 112 countries in 2021. Interested in joining our team? Check out our open job postings on careers site and apply directly today! https://www.flexport.com/careers/jobs/

GrubMarket is the AI-powered technology enabler and digital transformer of American Food Supply Chain industry. Our mission is to build and provide the eCommerce and software technologies to this industry, to transform this completely offline and highly manual industry into modernized online industry powered by software technologies, and improve the efficiency of American food supply chain.

The trucking and logistics industry provides the backbone of the economy, but the payments infrastructure on which it runs is broken; the existing suite of payment tools is outdated, difficult to use, prone to fraud, and saddled with hidden fee structures. AtoB is building Stripe for Transportation — modernizing the payments infrastructure for trucking and logistics, where capital movement occurs quickly and transparently. Our flagship product is the AtoB Fuel Card, a zero-fee fuel card accepted anywhere built for fleets of all shapes and sizes.

Our software allows drones to fly indoors and collect analytics, helping warehouses automate inventory collection.

Experience cutting-edge route optimization with Zeo, a versatile platform designed for both mobile and web. Our innovative app, trusted by over 1 million drivers across 146 countries, revolutionizes last-mile delivery by minimizing delivery times and reducing costs. Zeo Fleet, an essential tool for fleet managers and businesses, offers a seamless, no code solution to manage and assign stops to drivers, streamlining setup in under 15 minutes. Join 5,000+ businesses that rely on Zeo for daily route planning. Zeo caters to a diverse range of industries including last-mile delivery, waste management, healthcare, home services (like lawn mowing, pool maintenance, handyman services, HVAC), real estate, building inspection, and national park service. Key features of Zeo include advanced stop assignment, efficient route optimization, real-time driver tracking, comprehensive proof of delivery tracking, effective load assignment, and precise geo-fencing for drivers. Choose Zeo for a smarter, more efficient routing solution.

Attain is a one-stop shop for convenience store owners to buy inventory across all their suppliers with higher reliability, price transparency, and product discovery. On average, store owners buy products from over 10-15 different suppliers each week. This painful process involves shopping in massive warehouses or spending hours working with wholesaler’s sales representatives (who sometimes don’t even show up). As a result, stores waste countless hours ordering products through extremely inefficient and tedious processes. These store owners are also severely impacted by inventory shortages and revenue loss which many times results in them downsizing their business or shutting them down completely. Attain solves this problem by providing a single app to purchase products across all of their suppliers, resulting in a one-stop shop for inventory. By aggregating inventory across a multitude of suppliers and wholesalers, Attain helps stores save significant time and money while allowing them to focus on what they do best - growing their businesses. Feel free to reach out at founders@joinattain.com!

EasyPost is the missing API that makes it quick and painless to integrate shipping into your application. Some of the biggest names in retail rely on EasyPost to ship faster, smarter and cheaper. We manage the headaches involved with dated carrier technology so our customers can focus on what makes their business great. Integrate once with EasyPost and seamlessly add carriers, generate shipping labels, track packages in near real-time and insure your shipments. EasyPost is growing fast! Check out our jobs page and join the excitement: https://www.easypost.com/jobs

At Response, we simplify how ops teams manage indirect spend—everything from office supplies to maintenance materials and packaging. Our platform streamlines procurement, cutting ordering and approval times by up to 92% and helping companies save up to 13% by centralizing purchases with their existing vendors.