AI (Artificial Intelligence) Startups funded by Y Combinator (YC) in Boston 2025

March 2025

Browse 7 of the top AI startups funded by Y Combinator. Headquartered in Boston, these are some of the hottest and fastest-growing startups.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Nextera Robotics
    Nextera Robotics
    Y Combinator LogoS2020
    Active • 15 employees • Boston, MA, USA
    Nextera Robotics is an AI-native Robotics and Industrial Automation company founded at MIT.
    artificial-intelligence
    autonomous-delivery
    deep-learning
    robotics
    construction
  • Perceptive Technologies
    Perceptive Technologies
    Y Combinator LogoW2020
    Active • 25 employees • Boston, MA, USA
    Stealth-mode, rapidly scaling, venture-backed startup at the vanguard of automated robotic surgery revolution -- just closed our Series A round. We are improving access to dental care in underserved populations by combining novel imaging technology with AI and surgical robotics to automate surgery in the $452B dental industry. We are bringing a new imaging modality to dentistry which can see inside teeth and below the gingiva all without the need for x-rays. AI is used to diagnose decay and plan treatment. Automated robotics reduces the time for surgery down to one minute, reducing patient discomfort and saving time and reducing cost for the dentist. YC 2020, Winner of the Forsyth DenTech 2021 CareCaptial award
    robotics
    health-tech
    medical-devices
    ai
  • Helix Nanotechnologies
    Helix Nanotechnologies
    Y Combinator LogoW2017
    Active • 16 employees • Boston, MA, USA
    Technology finds information and delivers physical products to us almost instantly. mRNA does the same for biology. At HelixNano, we see a world where treatments are cheap, progress is decentralized, and you can modify biology at the push of a button. By focusing on mRNA improvements from first principles, we’re getting there faster than we thought. Experiments that used to take months or years can be done in weeks and cost thousands instead of millions. The rate limiting step for our progress is now scientific curiosity. Rigid hierarchies and top-down decisions will miss the magic. Some of our most powerful technologies started out as side projects of junior team members. At HelixNano, every individual scientist can have a massive impact on the company's direction. And the more diverse our team, the faster we’ll find the really cool ideas. We've started rolling out some of our new tech — moving a COVID-19 vaccine candidate for the immunocompromised towards the clinic, and testing an intervention with massive environmental impact. But we’re scientists at heart, and team focus is solidly on the horizon.
    artificial-intelligence
    biotech
    genomics
    nanotechnology
  • Alpha Vantage
    Alpha Vantage
    Y Combinator LogoS2018
    Active • 8 employees • Boston, MA, USA
    Alpha Vantage provides enterprise-grade financial market data through a set of powerful and developer-friendly data APIs and spreadsheets. Whether you need traditional asset classes (e.g., stocks, ETFs, commodities), economic metrics, foreign exchange rates, cryptocurrencies, fundamental data or even technical indicators, Alpha Vantage is your one-stop shop for global market data delivered through REST APIs.
    artificial-intelligence
    developer-tools
    saas
    analytics
    api
  • NuMind
    NuMind
    Y Combinator LogoS2022
    Active • 6 employees • Cambridge, MA, USA
    NuMind is a tool for data scientists, data analysts, but also software engineers to create custom NLP models. For example, a recruiting company uses NuMind to find which job offers best match a given resume. Etienne (CEO) was head of Machine Learning at Wolfram Research, and Samuel (CTO) co-founded Make.org (8M users). NuMind originated from our own frustration when developing NLP models. Leveraging large language models similar to GPT-3, NuMind allows to complete NLP projects at least 10x faster than before. We launched a private beta August 2 and had 9 paying customers one month later.
    aiops
    artificial-intelligence
    machine-learning
    nlp
  • FlyCode
    FlyCode
    Y Combinator LogoS2022
    Active • 7 employees • Boston, MA, USA
    FlyCode Dunning & Payment Management AI that helps subscription merchants maximize revenue. We reduce passive churn by managing payment failures intelligently. We’re Jake, Etai, and TD and we’re building FlyCode. TL;DR: If you sell SaaS or B2C subscriptions, we’re here to help you recover lost revenue due to failed payments and involuntary churn. ‘Involuntary’ or ‘Passive’ churn is a hidden Revenue Killer 💳 for Subscription Businesses ❌ THE PROBLEM: Recovering Failed Payments is Complex Involuntary churn refers to the loss of subscribers due to payment failures, not due to them actively canceling. While it is both possible and a worthwhile strategy to attempt to win back a customer during the cancellation process — involuntary churn is not intentional and in most cases, your customers aren’t even aware that their payment failed. 💰 Bottom line? Effective payment optimization does reduce involuntary churn and will increase ARR by as much as 5-10% FLYCODE SOLUTION 💡 FlyCode leverages ML and AI to provide Payment Optimization and smart payment retries to maximize subscription revenue and reduce churn. We apply a unique model tailored to each Merchant and their customers to ensure optimal results. ⚡️Automatically recover failed subscription payments and reduce passive churn ⚡️Use ML & AI based payment optimization to find the best time to charge your customers ⚡️ Improve customer experience by coordinating payment retries with customer emails/SMS 🛠️ We support OOTB + Custom Integrations for Merchants and White-Label for Platforms
    fintech
    payments
    e-commerce
    subscriptions
    ai