Crypto / Web3 Startups funded by Y Combinator (YC) in New York 2025

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OpenSea is building the world’s most trusted and inclusive peer-to-peer NFT marketplace. OpenSea makes minting, purchasing and selling NFTs frictionless, and offers multi-chain options for creators and collectors of all kinds to own and shape their relationships directly. Headquartered in New York, the OpenSea leadership team comes from Google, Palantir, Lyft, Uber, Stanford and Berkeley. Investors include a16z, Paradigm, Coatue.

Notabene helps businesses perform crypto transactions in a regulatory compliant way. Think of us as the SWIFT network for Crypto. New global regulations for crypto transactions are here and will be enforced over the next year. Businesses now have to follow strict rules similar to banks, or shut down. We provide a SaaS platform that allows businesses to perform due-diligence on their counter-parties and manage the risk of incoming and outgoing transactions.

SpruceID lets users control their data across the web. Instead of people signing into platforms, we imagine platforms should sign into people’s data vaults. We implement this pattern into digital wallet ecosystems for governments, enterprises, and blockchains. We believe that architectures that enable individual autonomy in the digital world are necessary for free societies and dynamic economies to thrive.

Hiro System builds developer tools for Bitcoin L1 and the Stacks L2 (layer-2). Stacks is a Bitcoin layer for smart contracts; it's an open-source project with an ecosystem of independent entities. Hiro serves 350M+ monthly API requests and thousands of crypto users on dev products.

Decent's core product,[The Box](https://decent.xyz/), enables 1-click transactions using any token across chains. For example, a user can purchase an Optimism NFT off primary or secondary sales using USDC on Arbitrum. As applications splinter across an increasing number of rollups and app chains, wallets and dapps will have to meet users at their point of liquidity vs. expecting users to jump through hoops to arrive with tokens on the correct network.

EthosX is a decentralized finance platform creating end-to-end financial derivatives on blockchains. No centralized exchanges, clearinghouses, depositories, clearing banks, CSD participants etc. required. We are starting with cryptocurrency options first, with the intention to move towards other crypto derivatives and traditional finance derivatives eventually. For example, one can buy a bitcoin hedging token directly from EthosX without involving any exchange or counterparty and earn profits when the bitcoin price is falling (similar to a put option). It is perpetual and is completely on-chain, end-to-end. It is held as a token in wallets and can be sold/transferred to anyone at any time. At institutional level, using EthosX’s options infrastructure two hedge funds can trade high-value on-chain options with each other directly without involving any banks or brokers with zero counterparty risk and zero settlement risk. We are also providing derivatives infrastructure to other crypto companies who want to use these products as a part of a larger package to their customers. Global derivatives ecosystem is broken. Derivatives trading in traditional finance has way too many gatekeepers and intermediaries. Crypto was supposed to be free of these issues and a solution to all of this, but it is itself getting more and more centralized with disastrous consequences. We at EthosX intend to pick the best of both worlds and change the way retail and institutional financial derivatives are traded world over.

Lyra is a crypto-native virtual card provider that allows users to easily create cards and fund them with cryptocurrency. Create virtual cards directly from your browser through our Chrome extension for all your purchases and subscriptions.

Blockscope is a Web3 data platform that enables anyone interested in on-chain data to quickly spin up live or historical data pipelines (for blocks, event, transaction, wallets, token, NFTs, etc). Similar to AWS, users have access to variety of managed software services to analyze, interact with or inject captured data into their apps. Our platform is built around the core idea of off-loading the on-chain data that our customers need for their Web3 apps, and reliably storing them for quick access/use. We offer products on top of the core data we index for our customers. Some of these services are contract analytics, wallet profiling, events & transactions database as a service, push notifications, webhooks, and developer tools. Our mission is to enable everyone to easily access and consume on-chain data!