Enterprise Software Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2025

January 2025

Browse 12 of the top Enterprise Software startups funded by Y Combinator. Headquartered in the San Francisco Bay Area, these are some of the hottest and fastest-growing startups.

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  • Checkr
    Checkr (s2014)Active • 800 employees • San Francisco, CA, USA
    Checkr builds people infrastructure for the future of work. And we believe everyone should have a fair chance to work. That's why we've designed a faster—and fairer—way to screen job seekers. For more information on our mission and products, visit http://checkr.com.
    compliance
    hr-tech
    api
    enterprise-software
    ai
  • HelloSign
    HelloSign (w2011)Acquired • 100 employees • San Francisco, CA, USA
    We believe that the way business gets done today is broken. That’s why we’re dedicated to simplifying work for everyone - from small startups to large enterprise companies. Millions of individuals and over 65,000 companies world-wide trust the HelloSign platform – which includes eSignature, digital workflow and electronic fax solutions – to automate and manage their most important business transactions. With a sharp focus on user experience and a lust for innovation, HelloSign is on a mission to Simplify Work.
    saas
    enterprise-software
  • Apero Health
    Apero Health (s2019)Active • 24 employees • San Francisco, CA, USA
    We help healthcare companies run their practices. Eligibility, BI, claims, patient payments? Shoot us an email at founders@aperohealth.com Apero is a Y-Combinator-backed startup based in San Francisco bringing transparency and ease to medical billing. As one of the top startups from the Summer 2019 Y Combinator batch, we have raised from well-known investors including the creator of Gmail Paul Buchheit and the founders of Doctor on Demand, Gusto and Reddit, and serve startups that have raised over $1B in Venture Capital. The founding team are Stanford CS and Berkeley grads and include the CTO of Doctor on Demand having helped raised $240m and process millions of video calls. We are also hiring for engineers and product-minded operations people interested in giving price transparency to patients and providers. We serve practices nationwide, and integrate with leading EHRs as well.
    health-tech
    finance
    digital-health
    enterprise-software
  • Gridware
    Gridware (w2021)Active • 50 employees • Walnut Creek, CA, USA
    Gridware exists to enhance and protect the mother of all networks: the electrical grid. The grid touches everyone and makes our modern economy possible. But it’s also fragile. When the grid is compromised, everything grinds to a halt, and the consequences can be dire: wildfires burn, land is destroyed, property is damaged, progress stops, and lives are lost. Our team builds smart sensors that help utility companies to immediately detect, find, and fix outages and take steps to prevent new outages, and other related disasters, from happening at all. The need for power will only increase. We protect the grid of today while we build the grid of tomorrow. Gridware is privately held and backed by the best climate-tech and Silicon Valley investors. We are headquartered in the Bay Area in northern California.
    hardware
    climate
    energy
    enterprise-software
  • Rulebricks
    Rulebricks (w2021)Active • 2 employees • Los Altos, CA, USA
    Many workflow builders and automation tools have support for adding logic to your processes, but get complicated quick– to the point where process owners are unable to edit them directly and require specialist services. Rulebricks separates decision-making logic from your workflows, giving your team a clear visual, spreadsheet-like interface to manage the changing rules that drive your business, and use those rules as API endpoints, visual forms, and in automation tools like Zapier.
    developer-tools
    saas
    b2b
    workflow-automation
    enterprise-software
  • MindsDB
    MindsDB (w2020)Active • 33 employees • San Francisco, CA, USA
    MindsDB is a fast-growing AI startup headquartered in San Francisco, California. As a leading innovator bringing AI and Data together, our passion is empowering companies to easily build AI capabilities that can Think, Understand and Orchestrate: enabling teams to move from prototyping & experimentation to production in a fast & scalable way. MindsDB was founded in 2017 by Adam Carrigan and Jorge Torres, inspired by Ian M. Banks's Culture series, in which super AI systems called Minds collaborate with other forms of life to accomplish incredible goals. Starting as an Open-Source project, MindsDB has grown to be one of the most widely used AI-Data platforms in the world, with a growing community and more than 700 contributor developers from every corner of the globe. We are backed with over $55M in funding from Mayfield, Benchmark, YCombinator, and nVidia. MindsDB is also recognized by Forbes as one of America's most promising AI companies (2021) and by Gartner as a Cool Vendor for Data and AI (2022).
    artificial-intelligence
    developer-tools
    machine-learning
    open-source
    enterprise-software
  • Leena AI
    Leena AI (s2018)Active • 500 employees • Winslow St, Redwood City, CA 94063, USA
    HR/IT/Finance professionals spend 50% of their time answering employees' questions and tickets. It’s even worse on the employee side, they have to wait for a long time for simple answers. We are live with 500 customers like Coca-Cola, Sony, Puma, Vodafone, Nestle, P&G, Airbnb, etc. We have raised over $40M from top VCs like Bessemer, Greycroft, Elad Gil, etc. Leena AI consumes company’s enterprise knowledge & starts answering all employee questions just like a human would. It can even answer complex personalized questions like Why is my salary less this month? Employees can access Leena AI from commonly used UIs like MS Teams or Slack.
    artificial-intelligence
    generative-ai
    chatbot
    enterprise-software
    ai-assistant
  • Docker
    Docker (s2010)Active • 201 employees • San Francisco, CA, USA
    Docker is the world’s leading software container platform. Developers use Docker to eliminate “works on my machine” problems when collaborating on code with co-workers. Operators use Docker to run and manage apps side-by-side in isolated containers to get better compute density. Enterprises use Docker to build agile software delivery pipelines to ship new features faster, more securely and with confidence for both Linux and Windows Server apps.
    open-source
    devops
    enterprise-software
  • Confident LIMS
    Confident LIMS (s2015)Active • 17 employees • Palo Alto, CA, USA
    Confident LIMS is a leading Laboratory Information Management System (LIMS) serving high-throughput labs in regulated industries. Confident LIMS is a B2B Software-as-a-Service (SaaS) platform with strong network effects among our lab customers and their testing clients. We currently serve >60% of the legal cannabis industry in the United States and are expanding into mainstream agriculture, food & beverage, and environmental industries. In early 2022, we pivoted away from seeking to be the leading online B2B wholesale marketplace in the legal cannabis industry to be the best LIMS in the world in the agriculture, food & beverage, environmental and industrial chemicals industries.
    saas
    b2b
    cannabis
    compliance
    enterprise-software
  • Optery
    Optery (w2022)Active • 20 employees • Walnut Creek, CA, USA
    Optery is automated opt out software, and we serve individuals, families and businesses. With Optery, you can remove yourself from hundreds of data brokers that are posting and selling your home address, phone number, email and other private information on the internet. Optery was awarded"Editors' Choice" by PCMag as the most outstanding product in its category in 2022, 2023, and 2024, was a winner in Fast Company's Next Big Things in Tech for Security and Privacy in 2023, and has received numerous Cybersecurity Excellence awards. Optery prevents phishing and social engineering, identity theft and fraud, online stalking and harassment, doxxing, and prevents people's private information from showing up in Google search results. Anyone can create a free account to receive a personalized Exposure Report with live screenshots summarizing where your information is being posted and sold online. Optery then provides free tools for self-service removals, or you can upgrade to a paid plan, and Optery will remove the profiles for you. Optery for Business serves enterprises removing personal information from the internet for their employees and executives, and offers an API enabling application developers to embed data broker scanning and removal technology into their applications.
    saas
    consumer
    security
    privacy
    enterprise-software
  • Pivot
    Pivot (s2022)Active • 2 employees • San Francisco, CA, USA
    Pivot helps you visualise, analyse and model your company's financial data way faster than Excel.
    saas
    finance
    b2b
    productivity
    enterprise-software
  • WorkLife (w2015)Acquired • 2 employees • San Francisco, CA, USA
    WorkLife is a web app that helps teams have more productive meetings. There are over 3 Billion meetings/year in the U.S. and studies show 50% of that time is completely wasted. WorkLife helps you reclaim that time by helping you and your team adopt good meeting habits - create agendas, stay on track during the meeting, and ensure next steps get done afterwards. Most people spend the majority of their waking hours at work, and way too many of those hours in unproductive meetings. Your work life is a big portion of your life -- and the happier and more productive you are at work, the more fulfilled and energized you are in your life. Better Work = Better Life.
    saas
    productivity
    collaboration
    enterprise-software