Health Tech Startups funded by Y Combinator (YC) in the San Francisco Bay Area 2025

January 2025

Browse 38 of the top Health Tech startups funded by Y Combinator. Headquartered in the San Francisco Bay Area, these are some of the hottest and fastest-growing startups.

We also have a Startup Directory where you can search through over 5,000 companies.

  • Lucira Health
    Lucira Health (w2015)Public • 43 employees • Emeryville, CA, USA
    Diassess Inc. is revolutionizing the way infectious diseases are prevented, diagnosed, and monitored by developing the tools necessary to empower people to become knowledgeable about their health. We produce inexpensive, disposable health diagnostic hardware that transforms any smartphone into a portable, real-time health-monitoring device for rapid, accessible, multiplexed analysis of bodily fluids anywhere in the world.
    health-tech
    diagnostics
  • CareMessage
    CareMessage (w2014)Active • 45 employees • San Francisco, CA, USA
    CareMessage is the technology non-profit building the largest patient engagement platform for low-income populations in the United States. Powered by the Health Equity Engine™, the platform enables organizations to combine messaging, data, and interoperability to increase access to care, improve clinical outcomes, and address social drivers of health. With 20 million patients reached since 2013, CareMessage is the only patient engagement solution proven to improve health equity at scale. The team, many with lived experiences in these communities, leverages a nonprofit model to reinvest revenue into impact. CareMessage is the partner of choice for organizations committed to advancing health equity.
    health-tech
    digital-health
  • Memora Health
    Memora Health (w2018)Active • 115 employees • San Francisco, CA, USA
    Memora Health helps healthcare organizations digitize and automate complex care workflows, making them simple for patients and clinicians to navigate. Memora ingests existing data on clinical workflows, converts them into cohesive messaging journeys that guide patients through their care episodes, and automates the completion of simple follow-up tasks in the EMR. Memora's platform reduces care team notifications by nearly 40%, has a >70 average NPS, and has improved clinical outcomes across various populations. Contact us at info@memorahealth.com
    health-tech
    digital-health
    ai
  • BrainKey
    BrainKey (w2019)Active • 12 employees • San Francisco, CA, USA
    BrainKey is an AI-driven digital healthcare company with a mission to create a world free from dementia. The company specializes in developing advanced clinical technologies that empower longevity physicians to detect and prevent cognitive decline and other brain longevity challenges. By analyzing brain MRI and biomedical data, BrainKey provides highly accurate and personalized brain health insights, supporting physicians in delivering tailored care for brain longevity. BrainKey's AI-powered platform streamlines diagnostics and reporting, improving both clinical outcomes and financial efficiency across the continuum of brain health care. Short Clip about BrainKey from the BBC: https://www.youtube.com/watch?v=ioSgvROTP0E
    neurotechnology
    health-tech
    digital-health
    ai
  • Apero Health
    Apero Health (s2019)Active • 24 employees • San Francisco, CA, USA
    We help healthcare companies run their practices. Eligibility, BI, claims, patient payments? Shoot us an email at founders@aperohealth.com Apero is a Y-Combinator-backed startup based in San Francisco bringing transparency and ease to medical billing. As one of the top startups from the Summer 2019 Y Combinator batch, we have raised from well-known investors including the creator of Gmail Paul Buchheit and the founders of Doctor on Demand, Gusto and Reddit, and serve startups that have raised over $1B in Venture Capital. The founding team are Stanford CS and Berkeley grads and include the CTO of Doctor on Demand having helped raised $240m and process millions of video calls. We are also hiring for engineers and product-minded operations people interested in giving price transparency to patients and providers. We serve practices nationwide, and integrate with leading EHRs as well.
    health-tech
    finance
    digital-health
    enterprise-software
  • Darmiyan
    Darmiyan (s2017)Active • 8 employees • San Francisco, CA, USA
    Novel quantitative virtual microscopy for early detection of Alzheimer's disease from non-invasive MRI.
    artificial-intelligence
    machine-learning
    health-tech
    diagnostics
  • Pair Team
    Pair Team (s2019)Active • 78 employees • San Francisco, CA, USA
    Pair Team cares for the highest-need Medicaid recipients through a community-led, virtual care model. We take responsibility for the whole person by addressing not just clinical needs, but also health-related social needs such as housing instability and food access. We partner with local community-based organizations like shelters and safety net providers to coordinate care alongside our multidisciplinary care team to improve the wellbeing of underserved individuals and communities.
    health-tech
    workflow-automation
    digital-health
    healthcare
    healthcare-it
  • Immunity Project (w2014)Active • 11 employees • San Francisco, CA, USA
    We're developing a free vaccine to cure HIV and AIDs. Immunity Project is a non-profit initiative dedicated to developing an HIV vaccine. We hacked the HIV life cycle to develop a vaccine that gives you the same power as HIV controllers. With success in our clinical trials, our goal is to give our vaccine away to the world for free.
    health-tech
    biotech
  • Sleep Reset
    Sleep Reset (w2017)Active • 8 employees • San Francisco, CA, USA
    Our mission is to improve quality of life for millions of people by providing easy, immediate access to the world’s best sleep care. Sleep Reset is a digital, personalized sleep clinic, available in a convenient mobile app for iOS and Android. Our program was designed in partnership with leading sleep experts from top sleep clinics and universities. The program improves sleep and reduces sleep anxiety with the most effective methods from sleep clinics, including strategies based on Cognitive Behavioral Therapy for Insomnia (CBT-i) which are proven to be more effective than sleeping pills. Throughout our program, each member is paired with a dedicated sleep coach who personalizes their program. It’s a life-long, sustainable solution to sleep better in weeks, with no pills or melatonin needed – which means no grogginess, side effects, or dependency. Sleep Reset has been covered in Forbes, TechCrunch, and INSIDER. The company was founded by Yunha Kim, a serial entrepreneur recognized by Forbes as 30 Under 30 and is backed by top Silicon Valley investors including YCombinator, Foundation Capital, New Enterprise Associates, Stanford University and 20+ founders/executives of leading companies.
    mental-health-tech
    sleep-tech
    consumer-health-services
    health-tech
    digital-health
  • Human Dx (s2012)Active • 11 employees • San Francisco, CA, USA
    The Human Diagnosis Project (also referred to as “Human Dx” or “the Project”) is a worldwide effort to build an open medical intelligence system that maps the steps to help any patient. By combining collective intelligence with machine learning, Human Dx intends to enable more accurate, affordable, and accessible care for all
    health-tech
    diagnostics
  • iollo
    iollo (s2022)Active • 3 employees • San Francisco, CA, USA
    iollo is an at-home metabolomics test to extend your healthy lifespan. We measure more than 500 biomarkers in blood and use AI to automatically match you with dietary, behavioral, and therapeutic interventions.
    generative-ai
    health-tech
    biotech
    enterprise
    ai
  • Lamar Health
    Lamar Health (w2021)Active • 6 employees • San Francisco, CA, USA
    $1 T is spent today on back office tasks such as patient triaging, intake, eligibility checks, prior auths and claims. Specialized knowledge is required to complete these tasks making them prone to errors and bottlenecked by staffing. Lamar Health takes the burden off of providers and intelligently automates these tasks. Starting with specialty medications.
    health-tech
    ai
  • Gradia Health
    Gradia Health (w2021)Active • 7 employees • San Francisco, CA, USA
    Our mission is simple: challenge archaic rules and implied medical conventions in healthcare to better serve patients and physicians. Gradia is the backbone of the entire patient experience, helping patients get personalized, high-touch care while also making clinics more money. With our software patients can stay informed/educated about the status of their care, easily communicate with their providers, and get direct access to a specialized virtual care team. Our software is currently at several clinics across the Southeastern US and helping thousands of patients get the care they deserve. 
    consumer-health-services
    health-tech
    telehealth
    digital-health
    healthcare
  • Scout (formerly Uh-Oh Labs)
    Scout (formerly Uh-Oh Labs) (w2022)Active • 12 employees • Santa Clara, CA, USA
    Digital health holds a lot of potential but is ignoring a growing problem: diagnostic testing. Without this data, providers and organizations will be limited in the services they can provide patients at home. Scout has developed a platform - Hub, test kits, and app - that delivers health testing at home with 10x lower development cost and 3x lower per-test price. Our patented tech also meets performance requirements for medical diagnoses and integrates with the current healthcare tech stack. Scout’s technology is poised to disrupt the outdated $33Bn diagnostic market by democratizing testing while dramatically improving the patient experience. Scout has received $16M in non-dilutive funding from the NIH and other organizations to fully de-risk our platform, and our pipeline includes a diverse test menu for primary care (e.g. respiratory and sexual health), wellness (e.g. gut health), and chronic conditions (e.g. certain cancers). We have already received FDA authorization for our platform in clinical settings and are planning to launch our flagship Scout Hub in 2024.
    consumer-health-services
    covid-19
    health-tech
    diagnostics
    consumer-products
  • Orchid
    Orchid (w2023)Active • 4 employees • San Francisco, CA, USA
    Orchid is an AI-powered Electronic Health Record (EHR) for independent mental health professionals that saves them time, money, and frustration by integrating core administrative workflows, streamlining clinical processes, and automating manual flows.
    artificial-intelligence
    mental-health-tech
    saas
    health-tech
    healthcare
  • Auricle
    Auricle (w2021)Active • 2 employees • Mountain View, CA, USA
    Auricle is a medical device company building a breakthrough neurostimulation implant to restore hearing in millions of patients who no longer benefit from hearing aids, get less than 60% on a word recognition test, but aren't prepared to make the jump to a cochlear implant. Our approach preserves remaining natural hearing through a reversible and less invasive surgery, addressing the key concerns that hold most patients back from getting a cochlear implant (currently the only treatment option for these patients). The company spun out of Stanford Biodesign having completed two acute human clinical studies demonstrating the approach will work. The team is now focused on developing their full implant system for their first clinical trial. Auricle addresses a currently unserved profile of hearing loss that affects a growing population of 3.5 million patients in the US and represents an immediately accessible $1.2B market opportunity with existing reimbursement.
    hard-tech
    neurotechnology
    health-tech
    medical-devices
    healthcare
  • Chorus Sleep
    Chorus Sleep (w2021)Active • 4 employees • San Francisco, CA, USA
    Chorus is a mobile app and coaching program that helps employees sleep better. We do this by combining sleep coaching, short lessons, and relaxing audio sessions that help employees, and their families, fall asleep faster and get better quality sleep through the night.
    mental-health-tech
    sleep-tech
    health-tech
  • Osmind
    Osmind (s2020)Active • 55 employees • San Francisco, CA, USA
    Osmind is the premier platform for clinicians and researchers advancing new life-saving mental health treatments. Today, mental health disorders are one of the leading causes of death worldwide, especially among young adults, and are tied to shortening lifespans. While there have been developments in new psychiatric medications since the first FDA approval in 1954, today there is a growing movement among clinicians, patients, and researchers who are recognizing the need to accelerate new science. The Osmind treatment platform is the first and only solution that solves specific challenges faced by neuropsychiatric clinics, spanning general psychiatry and interventional psychiatry (transcranial magnetic stimulation, ketamine, SPRAVATO®, psychedelic medicine, electroconvulsive therapy). The core electronic health record (EHR) technology is precisely developed for interventional treatment workflows and designed to support a strong therapeutic alliance, including journaling tools and assistance with health plan reimbursement, which is a significant access hurdle for millions of patients. Research from our platform is already helping to set new standards for mental health interventions. For example, in the largest published real-world analysis of ketamine infusion therapy for depression, we teamed up with Stanford University School of Medicine to share findings in the Journal of Affective Disorders (March 2022). We have multiple ongoing research studies leveraging our proprietary real-world data, including an even larger ketamine analysis leveraging machine learning to predict treatment outcomes. Osmind is a San Francisco–based public benefit corporation led by scientists, technologists, and psychiatrists. We are backed by top investors including DFJ Growth, General Catalyst, Future Ventures, Tiger Global, and Y Combinator.
    mental-health-tech
    saas
    health-tech
  • PicnicHealth
    PicnicHealth (s2014)Active • 100 employees • San Francisco, CA, USA
    Healthcare needs good data. At PicnicHealth, we are building deep real-world datasets fueling cutting-edge research while giving patients control of their own medical record data. These complete, clinically-rich datasets produce unique insights — across dozens of diseases — to ultimately get the right treatments into patients’ hands faster. We work directly with patients and leverage state of the art machine learning to transform messy medical records into structured, research-ready datasets. To date we’ve helped tens of thousands of patients securely access their records and proactively contribute to advancing research in diseases that impacts their lives.
    machine-learning
    health-tech
    digital-health
    healthcare
    nlp
  • Carrot Fertility
    Carrot Fertility (s2017)Active • San Francisco, CA, USA
    Carrot is a simple and affordable way for companies of any size to build or enhance their fertility benefit. Carrot can help with egg freezing, infertility treatments including in vitro fertilization (IVF), LGBT+ conception, and more. Fertility care is daunting and scary; our focus is on improving the employee experience during high impact moments related to fertility-- helping save time, money and stress.
    fertility-tech
    health-tech
  • Athelas
    Athelas (s2016)Active • 160 employees • Mountain View, CA, USA
    At Athelas, we're bringing simple, life-changing health care products to people around the globe. The future of healthcare is at the home - we are a team of technologists building the next generation of medical products at the intersection of hardware and software. We won’t stop until we’ve brought the world class tools of a hospital to your home. Athelas Remote Patient Monitoring (RPM) allows healthcare providers to monitor patient vitals like blood pressure, weight, and blood glucose without the patient ever having to enter a clinic, improving patient health and engagement, and reducing hospitalizations. We do this all through a beautifully integrated suite of devices and software tools that provides access to state-of-the-art technologies and groundbreaking AI powered analysis.
    health-tech
    medical-devices
    biotech
    healthcare
  • Lively, Inc.
    Lively, Inc. (w2017)Active • 195 employees • San Francisco, CA, USA
    Out-of-pocket healthcare costs are skyrocketing and every day, people all across America are forced to make difficult decisions about their health. Lively is the benefits solutions provider that gets it right. We designed our solutions to take the guesswork out of managing benefits. And our innovative features are built to simplify benefits administration and evolve with your business. Managing wellness and wealth takes more than a series of transactions. By combining robust features with unparalleled service, we make benefits administration effortless, even when time and energy are limited. Experience benefits administration as it should be with Lively. Go to www.livelyme.com to learn about how HSAs other modern employee benefits can help you and your team.
    fintech
    health-tech
    hr-tech
  • YourChoice Therapeutics
    YourChoice Therapeutics (w2019)Active • 3 employees • Berkeley, CA, USA
    YourChoice Therapeutics is revolutionizing the global contraceptive market. Our vision is to develop non-hormonal contraceptives to provide both women and men with birth control options that lack the associated risks of hormone-based options but are equally effective. Traditionally, it has been the women’s financial and health burden to have a contraceptive in place. Our first goal is therefore to bring a novel non-hormonal, on-demand and low cost female contraceptive to the market that will substantially improve their quality of life and well-being. Our second goal is to develop the first ever non-surgical and highly effective non-hormonal contraceptive for men. Currently, male contraception is limited to two main options – vasectomy or condoms. Having such options available to both women and men will globally allow for much better family planning, reduce the number of unwanted pregnancies including abortions and therefore reduce costs and ensure contraceptive health and well-being.
    health-tech
    biotech
  • Modern Health
    Modern Health (w2018)Active • 375 employees • San Francisco, CA, USA
    Modern Health is the leading mental wellness platform that combines clinically validated assessments, personalized stress management support, an international network of certified behavioral health coaches, and licensed therapists to deliver mental health support across a broad range of individual needs. Modern Health empowers employers to lead the charge in helping their employees be less stressed, more engaged, and happier through evidence-based technology and professional support. Modern Health has raised over $170M from top investors Battery Ventures, Kleiner Perkins, Founders Fund, and John Doerr and supports over 200 companies globally including Lyft, Pixar, SoFi, Credit Karma, Electronic Arts, Cooley, and Okta.
    mental-health-tech
    health-tech
  • ArchForm
    ArchForm (w2018)Active • 23 employees • Sunnyvale, CA, USA
    Archform is teeth aligner software startup that lets orthodontists create, design and 3D print aligners within their own offices. The idea is to provide orthodontists with a way to better compete against some direct-to-consumer teeth aligner startups and cut down on the cost of Invisalign.
    robotics
    health-tech
    medical-devices
    3d-printing
  • Segmed
    Segmed (w2020)Active • 32 employees • Palo Alto, CA, USA
    Segmed provides at-scale access to novel clinical data globally, offering millions of diagnostic-grade medical images to accelerate innovation and mature the evidence needs of life sciences and technology industry. ‍ Our solutions allow you to access a Real World Data (RWD) network to facilitate rapid discovery and investigational capability of imaging data, development of early disease detection & prediction models, improved patient recruitment and reduced operating burden to access therapeutic data ecosystem.
    health-tech
    healthcare
    ai
  • Ananya Health
    Ananya Health (s2021)Active • 5 employees • San Francisco, CA, USA
    Building a standard-of-care medical device to freeze abnormal cells before they become cervical cancer, in any clinic, anywhere in the world, at 1/10 the cost. -- Ananya Health is building a portable cryoablation unit designed for every primary care clinic in the world. Our beachhead application is cervical cancer prevention -- even though cervical cancer is easy to screen for, 80% of clinics worldwide lack the infrastructure and specialized staff to treat at the earliest stages. Our platform technology allows nurses and lower level health workers to treat at the point of care for 1/10 the cost of traditional ablation, and is the only cryo device that will help us achieve the WHO target to eliminate cervical cancer in our lifetime.
    hardware
    health-tech
    medical-devices
  • Blueberry Pediatrics
    Blueberry Pediatrics (w2018)Active • 15 employees • Mountain View, CA, USA
    Blueberry Medical provides concierge pediatric care with at-home medical diagnostics and an always-available team of Pediatricians. Blueberry handles twice as may illnesses as any other telemedicine provider and has proven to reduce ER costs by 50%.
    consumer-health-services
    health-tech
    telehealth
    pediatrics
    digital-health
  • Knowtex
    Knowtex (s2022)Active • San Francisco, CA, USA
    We’re on a mission to leverage AI and voice technology to solve inefficiencies and revenue leakage in our healthcare system. With the rise of EHRs, the manual documentation burden on doctors has never been higher, leading to burnout and fatigue and high attrition rates. Assigning the correct diagnosis and billing codes is crucial for proper reimbursement and patient care, but medical coding is becoming more and more complex each year with growing numbers of codes (over 145,000 now), and doctors are unsupported by current technology to keep up with its ever increasing requirements. $125 billion is left on the table each year by healthcare organizations due to improper documentation and coding. Knowtex creates visit notes with up-to-date and accurate reimbursement codes from doctor-patient conversations, allowing the doctor to focus on patient care and preventing revenue leakage for hospital systems through standardized, transparent, and accurate documentation.
    health-tech
    b2b
    productivity
    digital-health
    ai
  • RTHM
    RTHM (w2022)Active • 14 employees • Redwood City, CA, USA
    Current Description: RTHM provides virtual-first care for complex illness including Long COVID, ME/CFS, POTS, and mast cell activation. Many clinics focus on teaching patients how to better cope with symptoms, which is helpful, but we don’t stop there. We develop collaborations & partnerships so our patients access to the most promising testing and root-cause directed early therapies for their illness(es) with the goal of simplifying and streamlining the most efficient and effective clinical pathways so they can be scaled in the form of low cost online modules overseen remotely by clinicians. In conjunction with clinical care, RTHM operates a clinical lab and collects deep molecular data with robust clinical context to develop AI-powered diagnostics and better ways of predicting which treatments may work best for whom.
    consumer-health-services
    health-tech
    digital-health
    healthcare
    telemedicine
  • PlateJoy
    PlateJoy (s2015)Acquired • 11 employees • San Francisco, CA, USA
    PlateJoy uses 50 data points about how you eat and live to determine what you should be eating and provides customized meal plans and shopping lists to help you reach your goals. We provide a digital Diabetes Prevention Program, available for free to over 60M covered lives, paid for by insurers.
    health-tech
  • Mable
    Mable (s2021)Acquired • 7 employees • San Francisco, CA, USA
    Mable is a personalized migraine clinic using DNA to find and provide the right medication alongside continuous expert care Using our approach, patients have an 80% higher treatment satisfaction rate, have one extra day per week to enjoy their life and get 55% pain reduction.
    health-tech
    telehealth
    genomics
  • ListRunner (s2014)Acquired • 2 employees • Mountain View, CA, USA
    Listrunner is a service made to share patient information in a highly secure manner between authorized members of a clinical team– physicians, residents, interns, and medical students. Listrunner helps clinicians protect patient information by replacing manual processes, such as printed patient lists, which are untraceable and easily lost. Listrunner offers a secure alternative to unsecure practices, such as the use of SMS messages and camera phones to collect and share patient information between clinicians.
    health-tech
  • Science Exchange
    Science Exchange (s2011)Acquired • 50 employees • Palo Alto, CA, USA
    Science Exchange powers R&D outsourcing for the world’s top life sciences companies. Our marketplace gives scientists access to the innovation and research they need and our platform fully automates R&D outsourcing from source to pay so scientists can focus on what they love—science.
    saas
    health-tech
    biotech
    enterprise
  • MedXT
    MedXT (w2013)Acquired • 2 employees • San Francisco, CA, USA
    MedXT is the easiest way to manage medical images online. We make it easy for medical professionals to access and share their medical data safely and securely. We provide specialty tools such as RIS, PACS, and HL7 connectivity. The MedXT platform will power your imaging center, hospital radiology department, or radiology group. Learn more at https://www.medxt.com
    health-tech
    medical-devices
  • Sepsis Scout
    Sepsis Scout (w2018)Acquired • 5 employees • San Francisco, CA, USA
    Formerly known as Patchd Medical, now acquired by Cytovale. Wearable technology and AI to predict and prevent sepsis outside of hospital.
    deep-learning
    health-tech
    medical-devices