Machine Learning Startups funded by Y Combinator (YC) in New York 2025

February 2025

Browse 13 of the top Machine Learning startups funded by Y Combinator. Headquartered in New York, these are some of the hottest and fastest-growing startups.

We also have a Startup Directory where you can search through over 5,000 companies.

  • SPATE
    SPATE
    Y Combinator LogoS2018
    Active • 15 employees • New York, NY, USA
    Spate is your machine intelligence solution for finding the next big trend in Beauty and Food. For example, we spotted trends such as turmeric, face masks, and cold brew.
    machine-learning
    ai
  • Swayable
    Swayable
    Y Combinator LogoW2018
    Active • 30 employees • New York, NY, USA
    Swayable partners with the world's leading brands and advocacy groups to change minds, behaviors and attitudes. We are hiring in data science, full stack engineering, data visualization, design, and operations. We welcome unsolicited CVs from anyone, and especially encourage women and people from under-represented groups to talk to us.
    machine-learning
  • RedBrick AI
    RedBrick AI
    Y Combinator LogoW2022
    Active • 13 employees • Claymont, DE 19703, USA
    RedBrick AI's mission is to accelerate the adoption of artificial intelligence in radiology by building world-class software infrastructure. Currently, we are focused on helping radiology AI teams prepare high-quality datasets to train their algorithms. Radiology data, such as CT and X-ray scans, is an incredibly important source of truth in healthcare delivery. In fact, over 90% of all healthcare data is medical imagery! However, the global radiology workforce is overburdened. In the UK, for example, only 2% of radiology departments are able to fulfill their reporting requirements, and this trend is reflected worldwide. The acute state of radiology, coupled with the abundance of data, makes the use of AI in radiology a prime candidate. In 2022, $5.6 billion was invested in the development of AI in healthcare! However, a key hindrance to further adoption is the lack of sophisticated tools to build and deploy AI algorithms in clinical environments. This is the problem we’re focused on at RedBrick AI We're a team based out of Bangalore India, and USA. We're backed by leading institutional investors like Y Combinator and Peak XV (formerly Sequoia Capital India).
    aiops
    machine-learning
    healthcare
  • Toko
    Toko
    Y Combinator LogoW2022
    Active • 6 employees • New York, NY, USA
    Toko helps English learners in East Asia achieve speaking fluency. Through our mobile app, learners engage in short, realistic conversations with an AI and receive feedback on their grammar. With over 500 topics, learners can practice real-world scenarios ranging from small talk to workplace discussions. Toko offers a low-pressure environment to help learners build up their confidence. We make language fluency accessible to everyone - not just those with the means to meet 1:1 with a tutor. In Taiwan (our first market), Toko is ranked top 3 in the App Store for Education!
    ai-enhanced-learning
    education
    generative-ai
    machine-learning
    consumer
  • Concord Materials
    Concord Materials
    Y Combinator LogoS2021
    Active • 7 employees • New York, NY, USA
    SaaS automation tools, financing and marketplace for bulk construction materials
    fintech
    machine-learning
    marketplace
    insurance
    enterprise
  • Spoken
    Spoken
    Y Combinator LogoS2021
    Active • 7 employees • New York, NY, USA
    Spoken is a website where users compare buying options for the exact same product across multiple stores. We help our users never overpay online. Dane is a two-time technical YC founder; he sold his previous company, Parklet, to Greenhouse where he was VP of Platform for 4.5 years. Geoff is a Stanford MBA grad and sold his previous company Cabrio Taxi.
    artificial-intelligence
    machine-learning
    marketplace
    consumer
    e-commerce
  • Cerebrium
    Cerebrium
    Y Combinator LogoW2022
    Active • 4 employees • New York, NY, USA
    Cerebrium is a serverless infrastructure platform for AI applications. We make it easier for companies to build and deploy AI based applications. We offer Serverless GPU's with low cold start times, over 12 varieties of GPU chips, allow you to run large scale batch jobs, run realtime voice applications and much more. We are used by the teams at Tavus, CivitAI, Twilio and many more.  Customers typically experience 40% in cost savings when compared to using traditional cloud providers and can scale models to more than 10K requests per minute with minimal engineering overhead.
    artificial-intelligence
    machine-learning
    infrastructure
  • Axis
    Axis
    Y Combinator LogoW2022
    Active • 15 employees • New York, NY, USA
    Axis is a knowledge base of government regulations and officials that helps large companies do business in foreign markets. For example, if you want to operate in Saudi Arabia - our software tells you which laws you need to comply with and which officials you need approvals from. We currently cover major markets in Europe, Middle East, and Africa
    machine-learning
    b2b
    subscriptions
    regtech
  • Ploomber
    Ploomber
    Y Combinator LogoW2022
    Active • 7 employees • New York, NY, USA
    We are building a cloud platform to help companies deploy and scale AI applications.
    developer-tools
    machine-learning
    analytics
    ai
  • HOMLI
    HOMLI
    Y Combinator LogoS2022
    Active • 20 employees • New York, NY, USA
    Launched in 2022, HOMLI is a modern, scalable real estate brokerage that helps European consumers sell, rent, and buy real estate. We are building Europe's first 'Zestimate' platform to finally bring transparency around property prices and neighborhood dynamics to all consumers across Europe. We couple that with an in-house brokerage team that is more effective, more productive, and more pleasant to work with. We combine the most advanced technological innovations with a holistically new approach to operations to re-invent a brokerage industry that hasn't evolved in decades, and introduce a brand new real estate experience for European consumers.
    machine-learning
    real-estate
    consumer
    proptech
    ai
  • Coverage Cat
    Coverage Cat
    Y Combinator LogoS2022
    Active • 4 employees • New York, NY, USA
    Coverage Cat (https://www.coveragecat.com) is the best way for people to optimally insure against their risks for homeowners, auto, renters, and general liability insurance. Millions of wealthy but insurance-unfamiliar Americans have purchased policies that leave them vulnerable to million-dollar lawsuits and bankruptcy. Coverage Cat fixes their coverage and offers them cheaper premiums with a focus on the central question of insurance: "how much can you afford to lose?" This risk-first approach allows for policies with higher deductibles that no other insurer will sell you, and enables us to find the multi-million dollar coverage, for truly catastrophic events, that our users need.
    fintech
    machine-learning
    insurance
  • PowerX
    PowerX
    Y Combinator LogoW2020
    Acquired • 20 employees • New York, NY, USA
    PowerX AI powered sensors create proprietary data to save corporations 30% or more in energy, water and emissions. 
    machine-learning
    iot
    climate
    energy
  • Yhat
    Y Combinator LogoW2015
    Acquired • 17 employees • Brooklyn, NY, USA
    Yhat (YC W15, pronounced y-hat) was an end-to-end data science platform. Acquired by Alteryx (NYSE:AYX)
    artificial-intelligence
    machine-learning
    enterprise
    data-engineering