Machine Learning Startups funded by Y Combinator (YC) in the San Francisco Bay Area that are currently hiring 2025

January 2025

Browse 21 of the top Machine Learning startups funded by Y Combinator. Headquartered in the San Francisco Bay Area, these are some of the hottest and fastest-growing startups. Their teams are well-funded and actively hiring.

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  • Scale AI
    Scale AI (s2016)Active • 500 employees • San Francisco, CA, USA
    Scale accelerates the development of AI within organizations of any size to deliver critical business insights and operational efficiency. Its data-centric infrastructure platform leverages RLHF (Reinforced Learning with Human Feedback) to help organizations build the strongest AI models that supercharge their business, with customers across industries including Meta, Microsoft, U.S. Army, DoD’s Defense Innovation Unit, Open AI, General Motors, Toyota Research Institute, Brex, Instacart and Flexport.
    artificial-intelligence
    machine-learning
  • AgileMD
    AgileMD (s2011)Active • 15 employees • San Francisco, CA, USA
    At AgileMD, we are building the most advanced real-time predictive analytics and clinical algorithms platform for hospitals. Our cloud-based engine helps thousands of doctors and nurses around the country make medical decisions, so that every patient receives the highest quality and value of care based on the latest medical knowledge and data.
    machine-learning
    healthcare
  • PicnicHealth
    PicnicHealth (s2014)Active • 100 employees • San Francisco, CA, USA
    Healthcare needs good data. At PicnicHealth, we are building deep real-world datasets fueling cutting-edge research while giving patients control of their own medical record data. These complete, clinically-rich datasets produce unique insights — across dozens of diseases — to ultimately get the right treatments into patients’ hands faster. We work directly with patients and leverage state of the art machine learning to transform messy medical records into structured, research-ready datasets. To date we’ve helped tens of thousands of patients securely access their records and proactively contribute to advancing research in diseases that impacts their lives.
    machine-learning
    health-tech
    digital-health
    healthcare
    nlp
  • Tempo
    Tempo (w2015)Active • 158 employees • San Francisco, CA, USA
    SmartSpot is a post Series-A stealth startup backed by Founders Fund and Khosla Ventures that uses computer vision to deliver an unparalleled fitness training experience to your home. Our unique hardware solution gives amazing trainers the ability to see their class participants in real time and deliver detailed advice that was previously only possible in person.
    machine-learning
    consumer-health-services
  • Veryfi, Inc.
    Veryfi, Inc. (w2017)Active • 60 employees • San Mateo, CA, USA
    Veryfi is a Data Transformation Platform turning Documents into Data in Seconds with Accuracy & Speed Surpassing Humans. Veryfi gives you a fully integrated suite of data transformation products for you to securely capture, extract and transform bills, receipts and invoices into structured data for use in your app, website or backoffice. To learn more https://www.veryfi.com/ ITS TIME TO BUILD Veryfi's developer friendly toolkits enable superior products that automate Expense Management, AP/Bill Pay, Bookkeeping and provide consumer spend behavior in Market Research Invoices, Bills & POs 10 mins of data entry per invoice? No way! 5 seconds and it's done. Untap a goldmine of data down to line-items. Expense Receipts No more painful data entry for expense reimbursement. Bonus: comply with new data privacy regulations. FMCG/CPG Receipts Data is the new oil. Understand consumer spend across retail from SKUs in seconds. Hotel Folios Supercharge your travel & expense management product with a wealth of data minus the tedious data entry. W-2 Tax Form β Extract every drop of tax data from W2s in seconds. Including handwritten notes, checkboxes and multi-lines. Cards β Capture and extract data Credit Cards, Business Cards and Healthcare Insurance Cards in seconds. More: https://www.veryfi.com/
    artificial-intelligence
    machine-learning
    computer-vision
    api
  • Imbue
    Imbue (s2017)Active • 35 employees • San Francisco, CA, USA
    Imbue builds AI systems that reason and code, enabling AI agents to accomplish larger goals and safely work in the real world. We train our own foundation models optimized for reasoning and prototype agents on top of these models. By using these agents extensively, we gain insights into improving both the capabilities of the underlying models and the interaction design for agents. We aim to rekindle the dream of the *personal* computer, where computers become truly intelligent tools that empower us, giving us freedom, dignity, and agency to pursue the things we love.
    machine-learning
    data-engineering
    ai
  • Proven Group
    Proven Group (w2018)Active • 40 employees • San Francisco, CA, USA
    Proven is a data powered skincare company that creates personalized skincare products based on more than 47 factors about an individual's skin, genetic background, lifestyle and environment. Our formulations are rooted in the largest beauty database in the world, the proprietary Skin Genome Project, built in-house by Proven's cofounder Amy Yuan, a computational physicist from Stanford. The database has won MIT's AI Technology of the Year award and encompasses more than 20Million consumer datapoints and thousands of scientific articles on skin. Our challenge now is to tell the story of Proven, and share our industry leading personalized skincare products with the world.
    artificial-intelligence
    machine-learning
    consumer
    e-commerce
  • Klarity
    Klarity (s2018)Active • 128 employees • San Francisco, CA, USA
    Klarity is Enterprise AI that automates accounting and compliance processes for companies like DoorDash, CrowdStrike and Zoom. Klarity has two core capabilities: (1) understand documents like Orders, Invoices and Contracts to the same degree as a human, and (2) automate the following process - identifying outliers, matching, calculations and validations. Klarity reduces OpEx, delivers real-time turnaround and boosts accuracy.
    artificial-intelligence
    machine-learning
    saas
  • Sapling.ai
    Sapling.ai (w2019)Active • 2 employees • San Francisco, CA, USA
    Sapling offers an API and SDK to help businesses integrate language models into their applications. Its messaging assistant sits on top of CRMs and messaging platforms to help users more efficiently compose responses.
    artificial-intelligence
    deep-learning
    generative-ai
    machine-learning
    b2b
  • Short Story
    Short Story (s2019)Active • 120 employees • San Francisco, CA, USA
    Short Story is a style discovery platform to help petite women find clothes that fit. The average American woman is 5'4" and petite, yet this remains an enormously underserved segment. We’re a team of curators passionate about finding style, quality, and fit for petite women. Our mission is to remove the “ugh” from the shopping equation and support petite women in telling their stories, stylishly and confidently.
    machine-learning
    marketplace
    e-commerce
  • Rosebud AI
    Rosebud AI (s2019)Active • 10 employees • San Francisco, CA, USA
    Rosebud is building the AI Roblox. We will make it 1000X easier for a community of game devs to create and enjoy the games of their dreams. ‍ We’re a team of PhD researchers, creatives and engineers building the generative AI platform to enable game creation at the speed of thought. We believe all media creation will be done via generative methods in a few years. We're building that future.
    artificial-intelligence
    developer-tools
    generative-ai
    machine-learning
    gaming
  • MindsDB
    MindsDB (w2020)Active • 33 employees • San Francisco, CA, USA
    MindsDB is a fast-growing AI startup headquartered in San Francisco, California. As a leading innovator bringing AI and Data together, our passion is empowering companies to easily build AI capabilities that can Think, Understand and Orchestrate: enabling teams to move from prototyping & experimentation to production in a fast & scalable way. MindsDB was founded in 2017 by Adam Carrigan and Jorge Torres, inspired by Ian M. Banks's Culture series, in which super AI systems called Minds collaborate with other forms of life to accomplish incredible goals. Starting as an Open-Source project, MindsDB has grown to be one of the most widely used AI-Data platforms in the world, with a growing community and more than 700 contributor developers from every corner of the globe. We are backed with over $55M in funding from Mayfield, Benchmark, YCombinator, and nVidia. MindsDB is also recognized by Forbes as one of America's most promising AI companies (2021) and by Gartner as a Cool Vendor for Data and AI (2022).
    artificial-intelligence
    developer-tools
    machine-learning
    open-source
    enterprise-software
  • Replicate
    Replicate (w2020)Active • 27 employees • San Francisco, CA, USA
    artificial-intelligence
    developer-tools
    machine-learning
    community
    open-source
  • Roboflow
    Roboflow (s2020)Active • 50 employees • San Francisco, CA, USA
    Roboflow enables developers to make the world programmable. Use our tools to build better datasets (collect image, video / annotate), models (foundation and fine tuned small models), and deployments (self hosted, edge, APIs, SDKs) for computer vision. Over 250k developers, including those from over half the Fortune 100, build with our open source and hosted tools. Build with us: https://app.roboflow.com Hack with us: https://roboflow.slab.com/public/posts/roboflow-hackathons-external-u478m1iz Work with us: roboflow.com/careers
    developer-tools
    machine-learning
    computer-vision
    api
    ai
  • Promoted.ai
    Promoted.ai (w2021)Active • 12 employees • San Francisco, CA, USA
    Promoted.ai unifies search, native ads, and feed ranking for online marketplaces and scaled e-commerce apps to dramatically improve relevance (and revenue) using AI. We are a team of ex-Google, Meta, and Pinterest ads engineers. Our customers are publicly traded and late-stage marketplace companies like Eventbrite, Upwork, and Outschool. Our mission is to connect every buyer and seller.
    machine-learning
    marketplace
    b2b
    e-commerce
  • Openlayer
    Openlayer (s2021)Active • 6 employees • San Francisco, CA, USA
    Openlayer helps you test and monitor high-quality AI systems.
    aiops
    developer-tools
    generative-ai
    machine-learning
    ai
  • Slope
    Slope (s2021)Active • 16 employees • San Francisco, CA, USA
    Accept and reconcile B2B payments seamlessly.
    artificial-intelligence
    fintech
    machine-learning
    payments
    fraud-detection
  • Mach9
    Mach9 (s2021)Active • 15 employees • San Francisco, CA, USA
    Mach9 is at the forefront of leveraging advanced machine learning and computer vision techniques to transform geospatial data into actionable insights for urban development and infrastructure management. Our cutting-edge technology automates the detection and analysis of key urban features, aiding in the planning and maintenance of transportation networks.
    machine-learning
    computer-vision
    infrastructure
    ai
  • Dynamo AI
    Dynamo AI (w2022)Active • 40 employees • San Francisco, CA, USA
    End-to-end privacy, security, and compliance solutions to prepare your organization for emerging AI regulations.
    machine-learning
    privacy
    data-engineering
  • Invert
    Invert (w2022)Active • 25 employees • San Francisco, CA, USA
    We build software to manage, analyze, and optimize bioprocessing data. Our initial customers are bio-industrial companies, who produce various products in bioreactors.
    cellular-agriculture
    machine-learning
    synthetic-biology
    biotech
  • Phiar
    Phiar (s2018)Acquired • 12 employees • Redwood City, CA, USA
    At Phiar, we are building the first AI-powered AR navigation driving software solution that runs on a smartphone and in-vehicle displays, utilizing our ultra-lightweight road understanding AI that runs completely at-the-edge, in real-time, all on just a smartphone-level compute. Our mission is to enhance driving safety, facilitate more intuitive wayfinding, and connect drivers with their surrounding environments.
    artificial-intelligence
    machine-learning
    augmented-reality